CNRS Grenoble INP Université Grenoble Alpes


Fed3g Investissements d'Avenir Tec21 Institut Carnot PolyNat


Accueil > Recherche > Séminaires

04 Avril 2019 Roger Lentle (Massey Univ. NZ)

« Verifiable modelling of physical processing in the various compartments of the gut "

Jeudi 04 Avril 2019 de 14h à 15h salle de conférences (RDC) du bâtiment NANOBIO DCM, 570 rue de la chimie (badge pour entrer)

Résumé :
I discuss the rheological and physiological difficulties in predicting mixing and propulsion of digesta within the intestinal lumen. I also describe the use of spatiotemporal mapping to quantify movements in ex vivo segments of the intestinal wall in real time, the use of this data in computational fluid dynamic models to predict flow and mixing, and the concurrent use of dye marker excretion profiles to validate the models. Further I give an example of how discrepancies between the two can highlight previously unknown sources of mixing. Finally I discuss recent work of the stomach.


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